Cell-wide Metabolic Alterations Associated With Malignancy

Cell-wide Metabolic Alterations Associated With Malignancy

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as qyet anotherq general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo.Ebbels, T. M. D., 298a€“300, 307 Ebert, B. L., 236a€“237 Edwards, R. E., 303a€“304 Efeyan, A., 143 Eggermont, A., 167 Egia, A., 142 ... 243 Fang, A. Q., 319 Fang, M. Q., 116a€“118 Fang, Z., 81 Fantin, V. R., 301 Farag, M. A., 183, 196 Farmer, T. B. , 201a€“202, 268 Farquhar, G. D., ... 23a€“24, 29 Fellows, G. A., 301 Fendt, S. M., 183 a€“184 Feng, M., 5 Ferguson, D. J., 103a€“108 Fernandez, C. A., 189a€“191 Fernie, A. R., anbsp;...


Title:Cell-wide Metabolic Alterations Associated With Malignancy
Author:
Publisher:Academic Press - 2014-06-07
ISBN-13:

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